Why is the score for my gene or variant not available?
It can be that the variant you search is under hg19 or did not qualify for the QC filter of the most recent version of gnomAD or synvep database.
Can I score multiple variants or genes?
Unfortunately, no. We have limited server resources and cannot manage large data requests, however you can directly use our Python Package - symetrics which comes with a portable package symetrics.sqlite3. You can also use any programming language to interact with the database for a more specific and customized transaction.
Can I use Hg19?
This web application requires Hg38, however, the same Python Package can be used to perform a liftover.
Will there be a Web API for this?
Yes, but it is still under development.
How can I cite this work?
Please refer to the original paper of symetrics or Bundalian, L. et. al (2024). Symetrics [Computer software]. Retrieved from https://tools.hornlab.org/symetrics/.